体系评价/Meta阐发指周全搜集一切相干研讨并逐一停止严酷评价和阐发,阐发再用定性或定量分解的注册体例对材料停止处置得出综合论断的研讨体例。在指点学生的具体进程中发明初学者在进修进程中经常会碰着良多个性标题标题题目,本公家号特此开设专栏解答,步骤但愿能够或许或许和大师配合进修交换Meta阐发,示例配合生长,阐发若有不妥的地方,注册还请大师攻讦斧正。具体本期咱们将侧重先容Meta阐发的步骤注册流程。
比方: 1. A systematic review and meta-analysis of rehabilitation in patients with sepsis(表现PI)
A network meta-analysis of interventions to control myopia progression in children(表现PO) Minocycline in depressive symptoms: a meta-analysis of randomized controlled trials(表现PIS)
凡是标明该研讨的目标,能够或许因此问句或陈说句的情势,比方
干涉干与性meta阐发:The aim of this meta-analysis of randomized controlled trials is to evaluate the efficacy and safety of adjunctive minocycline for depressive symptoms regardless of the main psychiatric condition. Whether could IgA nephropathy patients benefit from omega-3 fatty acids treatment? How do the kidney function and daily proteinuria of IgA nephropathy patients change after taking omega-3 fatty acids comparing with placebos? 率的meta阐发:What is the prevalence of neuropathic pain in patients with symptomatic knee osteoarthritis? 也能够或许自问自答:What are the effects of the various optical, pharmacological and lifestyle interventions in preventing myopia progression in children? We aim to generate a clinically useful summary of the interventions based on their efficacy.
这局部内容中不须要给出完美的检索战略(可作为附件上传),首要描写检索的体例和检索词的关头词,比方:
We will search, with no time restrictions, the following databases for relevant English language literature: PubMed (MEDLINE), the Cochrane Central Register of Controlled Trials (CENTRAL) and Web of Science.The search string will be built as follows: 可替代(Osteoarthritis OR OA) AND (pain) AND (neuropathic OR nociceptive OR central sensitization OR DN4 OR painDETECT OR S-LANSS OR quantitative sensory testing). The electronic database search will be supplemented by a manual search of the reference lists of included articles. We will search articles in three electronic database including PubMed, EMBASE and Cochrane Library. All the English publications until 30 April 2018 will be searched without any restriction of countries or article type. Reference list of all selected articles will independently screened to identify additional studies left out in the initial search.
可上传完全检索战略的PDF文档,上传后则默许能够或许公然拜候,清算的格局以不#1、#2、#3的情势,具体能够或许参与课程。
相称因而论文背景局部的简化版,普通包含疾病的概述和风行病学数据、干涉干与办法的研讨近况与缺乏等信息 如:
Supracondylar humeral fracture(SCHF) is the extremely common pediatric fracture in children younger than 15 years, accounting for approximately 75% of all pediatric elbow injuries. It has been suggested that 96% of all SCHFs are extension-type injuries that occur during falls onto the outstretched hand, whereas between 1% and 2% occur through falls onto the olecranon with the elbow flexed. Supracondylar fractures, most commonly, are classified according to Gartland ’s criteria: types I (nondisplaced and stable), type II (hinged fractures with the posterior cortex intact), and type III (completely displaced). Depression in adults, and its treatment using cognitive remediation therapy.Cognitive remediation therapy is the general term for a kind of psychotherapy which focuses on correcting and changing patients' adaptations to benign cognition. Its main goal is the remediation of bad cognition, but the patient's emotions and the behavior can also be changed.
首要描写P,如Adults with depression (as diagnosed by a clinician, or using any recognized diagnostic criteria) will be included. 但在这里须要指出的是解除规范必然是在归入规范的规模外面再停止解除,不能呈现下述抒发如归入小于18岁,解除18岁以上(即便注册胜利也毛病多多,首要缘由是不规范的把握体例学)
这一局部首要描写I,可简单也可庞杂,可是尽能够能够或许或许切近成稿论文 Physical exercise was the main intervention (e.g. aerobic exercise, resistance exercise and multicomponent exercise program).
绝对干涉干与办法,首要描写对比办法
普通环境下咱们归入随机对比实验,则能够或许表述为Randomized controlled trials (RCTs) will be included.这一局部也能够或许对颁发时辰、说话范例等做限定如Randomized clinical trials will be included irrespective of blinding, publication status or language.,但不倡议对P或I做更多的描写
简单写一下称号,如overall survival (OS) and progression-free survival (PFS).或某个量表的变更如mean change in WOMAC pain,须要连系本身的研讨停止判定
描写终局目标的效应量,如二分类变量挑选RR/OR, 持续性变量挑选SMD/MD, 保存阐发材料选HR
与首要终局目标体例不异,首要填写体系评价的主要终局目标
普通有模版,先表现两人自力提取,第三人处理不合如Two authors will independently extract data. Any disagreement will be resolved by discussion until consensus is reached or by consulting a third author.同时最好加上须要提取哪些信息,如The following data will be extracted: author, year of publication, country where the study was conducted, study period, original inclusion criteria, total number of people included in the study, doses of progesterone and time of application, and mean cervical length.